A new study is the first to show a direct link between a high body-mass index and the risk of developing heart disease, according to British and Danish researchers.
Body-mass index, or BMI, is a measurement based on height and weight. People with a BMI of 18.5 to 24.9 are normal weight while those with a BMI of 30 or more are obese. Those in between are deemed overweight.
For the study, the researchers analyzed data from more than 75,000 people and found that those with a high BMI had a 26 percent increased risk of developing heart disease. Further analysis using genetic and other data showed that a BMI increase of four points increases the risk of heart disease by no less than 52 percent.
“By doing epidemiological studies combined with genetic analysis, we have been able to show in a group of nearly 76,000 persons that a high BMI is enough in itself to damage the heart,” Borge Nordestgaard, chief physician at Copenhagen University Hospital, said in a university news release.
“Studies have also suggested a relationship between heart disease and obesity, but that is not enough to prove any direct correlation. Obese people can share characteristics or lifestyle traits that have an influence on both the heart and weight. Or there can be a reverse causality, that is, if it is the diseased heart that causes obesity and not the other way round,” said Nordestgaard, who is also a clinical professor in the health and medical sciences faculty at the university.
Study co-author Dr. Nicholas Timpson, a lecturer in genetic epidemiology at the University of Bristol in England, noted in the news release: “In light of rising obesity levels, these findings are crucial to improving public health. Our research shows that shifting to a lifestyle that promotes a lower BMI will reduce the odds of developing the disease.”
Comment
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